Nagata M, Izumi Y, Ishikawa E, Kiyotake R, Doi R, Iwai S, Omahdi Z, Yamaji T, Miyamoto T, Bamba T, Yamasaki S.
Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity.
Proc. Natl. Acad. Sci. U S A. 114(16):E3285-E3294, 2017.
Ishikawa E, Mori D, Yamasaki S.
Recognition of Mycobacterial Lipids by Immune Receptors.
Trends Immunol. 38(1):66-76, 2017.
Ishikawa, E., Kosako, H., Yasuda, T., Ohmuraya, M., Araki, K., Kurosaki, T., Saito, T., Yamasaki, S.
Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1.
Nat. Commun. 7:12756, 2016.
Kiyotake, R., Oh-Hora, M., Ishikawa, E., Miyamoto, T., Ishibashi, T., Yamasaki, S.
Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses.
J. Biol. Chem. 290:25322-32, 2015.
Yonekawa, A., Saijo, S., Hoshino, Y., Miyake, Y., Ishikawa, E., Suzukawa, M., Inoue, H., Tanaka, M., Yoneyama, M., Oh-Hora, M., Akashi, K., Yamasaki, S.
Dectin-2 is a direct receptor for mannose-capped lipoarabinomannan of mycobacteria.
Immunity 41:402-13, 2014.
Miyake, Y., Ishikawa, E., Ishikawa T. and Yamasaki, S.
Self and nonself recognition through C-type lectin receptor, Mincle.
Self Nonself 1:310-13, 2010.
Ishikawa E, Miyake Y, Hara H, Saito T, Yamasaki S.
Germ-line elimination of electric charge on pre-T-cell receptor (TCR) impairs autonomous signaling for beta-selection and TCR repertoire formation.
Proc. Natl. Acad. Sci. USA. 107(46):19979-19984, 2010.
Ishikawa, E., Ishikawa, T., Morita, S. Y., Toyonaga, K., Yamada, H., Takeuchi, O., Kinoshita, T., Akira, S., Yoshikai, Y. and Yamasaki, S.
Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle.
J. Exp. Med. 206(13): 2879-2888, 2009.
Yamasaki, S., Matsumoto, M., Takeuchi, O., Matsuzawa, T., Ishikawa, E., Sakuma, M., Tateno, H., Uno, J., Hirabayashi, J., Mikami, Y., Takeda, K., Akira, S., Saito, T.
C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia.
Proc. Natl. Acad. Sci. USA. 106(6): 1897-1902, 2009.
Yamasaki, S., Ishikawa, E., Sakuma, M., Ogata, K. and Saito T.
Macrophage inducible C-type lectin is an ITAM-coupled activating receptor that senses damaged cells.
Nat. Immunol. 9(10): 1179-1188, 2008.
Yamasaki, S., Takase-Utsugi, M., Ishikawa, E., Sakuma, M., Nishida, K., Saito, T. and Kanagawa, O.
Selective impairment of FcεRI-mediated allergic reaction in Gads-deficient mice.
Int. Immunol. 20(10) 1289-1297, 2008.
Yamasaki, S., Ishikawa, E., Sakuma, M., Kanagawa, O., Cheng, A.M., Malissen, B. and Saito, T.
LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival.
Mol. Cell. Biol. 27(12): 4406-4415, 2007.
Yamasaki, S., Ishikawa, E., Sakuma, M., Ogata, K., Sakata-Sogawa, K., Hiroshima, M., Wiest, D.L., Tokunaga, M. and Saito, T.
Mchanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development.
Nat. Immunol. 7(1): 67-75, 2006.
Ishikawa, E., Nakazawa, M., Yoshinari, M. and Minami, M.
Role of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand in Immune Response to Influenza Virus Infection in Mice.
J. Virol. 79(12): 7658-63, 2005.
Yamasaki, S., Ishikawa, E., Kohno, M. and Saito, T.
The quantity and duration of FcRγ signals determines mast cell degranulation and survival.
Blood 103(8): 3093-3101, 2004.