石川 絵里 Eri Ishikawa

石川 絵里 Eri Ishikawa

業績

Nagata M, Izumi Y, Ishikawa E, Kiyotake R, Doi R, Iwai S, Omahdi Z, Yamaji T, Miyamoto T, Bamba T, Yamasaki S.
Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity.
Proc. Natl. Acad. Sci. U S A. 114(16):E3285-E3294, 2017.

Ishikawa E, Mori D, Yamasaki S.
Recognition of Mycobacterial Lipids by Immune Receptors.
Trends Immunol. 38(1):66-76, 2017.

Ishikawa, E., Kosako, H., Yasuda, T., Ohmuraya, M., Araki, K., Kurosaki, T., Saito, T., Yamasaki, S.
Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1.
Nat. Commun. 7:12756, 2016.

Kiyotake, R., Oh-Hora, M., Ishikawa, E., Miyamoto, T., Ishibashi, T., Yamasaki, S.
Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses.
J. Biol. Chem. 290:25322-32, 2015.

Yonekawa, A., Saijo, S., Hoshino, Y., Miyake, Y., Ishikawa, E., Suzukawa, M., Inoue, H., Tanaka, M., Yoneyama, M., Oh-Hora, M., Akashi, K., Yamasaki, S.
Dectin-2 is a direct receptor for mannose-capped lipoarabinomannan of mycobacteria.
Immunity 41:402-13, 2014.

Miyake, Y., Ishikawa, E., Ishikawa T. and Yamasaki, S.
Self and nonself recognition through C-type lectin receptor, Mincle.
Self Nonself 1:310-13, 2010.

Ishikawa E, Miyake Y, Hara H, Saito T, Yamasaki S.
Germ-line elimination of electric charge on pre-T-cell receptor (TCR) impairs autonomous signaling for beta-selection and TCR repertoire formation.
Proc. Natl. Acad. Sci. USA. 107(46):19979-19984, 2010.

Ishikawa, E., Ishikawa, T., Morita, S. Y., Toyonaga, K., Yamada, H., Takeuchi, O., Kinoshita, T., Akira, S., Yoshikai, Y. and Yamasaki, S.
Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle.
J. Exp. Med. 206(13): 2879-2888, 2009.

Yamasaki, S., Matsumoto, M., Takeuchi, O., Matsuzawa, T., Ishikawa, E., Sakuma, M., Tateno, H., Uno, J., Hirabayashi, J., Mikami, Y., Takeda, K., Akira, S., Saito, T.
C-type lectin Mincle is an activating receptor for pathogenic fungus, Malassezia.
Proc. Natl. Acad. Sci. USA. 106(6): 1897-1902, 2009.

Yamasaki, S., Ishikawa, E., Sakuma, M., Ogata, K. and Saito T.
Macrophage inducible C-type lectin is an ITAM-coupled activating receptor that senses damaged cells.
Nat. Immunol. 9(10): 1179-1188, 2008.

Yamasaki, S., Takase-Utsugi, M., Ishikawa, E., Sakuma, M., Nishida, K., Saito, T. and Kanagawa, O.
Selective impairment of FcεRI-mediated allergic reaction in Gads-deficient mice.
Int. Immunol. 20(10) 1289-1297, 2008.

Yamasaki, S., Ishikawa, E., Sakuma, M., Kanagawa, O., Cheng, A.M., Malissen, B. and Saito, T.
LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival.
Mol. Cell. Biol. 27(12): 4406-4415, 2007.

Yamasaki, S., Ishikawa, E., Sakuma, M., Ogata, K., Sakata-Sogawa, K., Hiroshima, M., Wiest, D.L., Tokunaga, M. and Saito, T.
Mchanistic basis of pre-T cell receptor-mediated autonomous signaling critical for thymocyte development.
Nat. Immunol. 7(1): 67-75, 2006.

Ishikawa, E., Nakazawa, M., Yoshinari, M. and Minami, M.
Role of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand in Immune Response to Influenza Virus Infection in Mice.
J. Virol. 79(12): 7658-63, 2005.

Yamasaki, S., Ishikawa, E., Kohno, M. and Saito, T.
The quantity and duration of FcRγ signals determines mast cell degranulation and survival.
Blood 103(8): 3093-3101, 2004.

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