業 績 PUBLICATIONS

2021年

  1. Lu X, Hosono Y, Nagae M, Ishizuka S, Ishikawa E, Motooka D, Ozaki Y, Sax N, Maeda Y, Kato Y, Morita T, Shinnakasu R, Inoue T, Onodera T, Matsumura T, Shinkai M, Sato T, Nakamura S, Mori S, Kanda T, Nakayama EE, Shioda T, Kurosaki T, Takeda K, Kumanogoh A, Arase H, Nakagami H, Yamashita K, Takahashi Y, Yamasaki S.
    Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients.
    J. Exp. Med. 218:e20211327, 2021

  2. Torigoe S, Schutt CR, Yamasaki S.
    Immune discrimination of environmental spectrum through C-type lectin receptors.
    Int. Immunol. 33:847-851, 2021

  3. Kitai Y, Sato K, Tanno D, Yuan X, Umeki A, KasamatsuJ, Kanno E, Tanno H, Hara H, Yamasaki S, Saijo S, Iwakura Y, Ishii K, Kawakami K.
    Role of Dectin-2 in the Phagocytosis of Cryptococcus neoformans by Dendritic Cells.
    Infect. Immun. 89: e0033021, 2021

  4. Iijima A, Kanemaru K, Wang Y, Nabekura T, Nakamura Y, Fujisawa Y, Mori D, Ohmuraya M, Yamasaki S, Tahara-Hanaoka S, Shibuya A.
    Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells.
    Biochem. Biophys Res. Commun. 561: 101-105, 2021

  5. Trujillo-Viera J, EI-Merahbi R, Schmidt V, Karwen T, Loza-Valdes A, Strohmeyer A, Reuter S, Noh M, Wit M, Hawro I, Mocek S, Fey C, Mayer AE, loffler MC, Wihelmi I, Metzger M, Ishikawa E, Yamasaki S, Rau M, Geier A, Hankir M, Seyfried F, Klingenspport M, Sumara G.
    Protein Kinase D2 drives chylomicron-mediated lipid transport in the interstine and promotes obesity.
    EMBO Mol. Med. 13: e13548, 2021

  6. Iizasa E, Chuma Y, Uematsu T, Kubota M, Kawaguchi H, Umemura M, Toyonaga K, Kiyohara H, Yano I, Colonna M, Sugita M, Matsuzaki G, Yamasaki S, Yoshida H, Hara H.
    TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation.
    Nat. Commun. 12:2299, 2021

  7. Yamamoto H, Tomiyama C, Sato K, Kasamatsu J, Takano K, Umeki A, Nakahara N, Miyasaka T, Kanno E, Tanno H, Yamasaki S, Saijo S, Iwakura Y, Ishii K, Kawakami K.
    Dectin-2-mediated initiation of immune responses caused by influenza virus hemagglutinin.
    Biomed. Res. 42: 53-66, 2021

  8. Lynch AT, Motozono C, Foster AJ, Kodar K, Dangerfield EM, Yamasaki S, Wedlock DN, Timmer MSM, Stocker BL.
    Trehalose diamide glycolipids augment antigen-specific antibody responses in a Mincle-dependent manner.

    Bioorg. Chem. 110: 104747, 2021

  9. Shiga M, Miyazaki J, Tanuma K, Nagumo Y, Yoshino T,  Kandori S, Neguro H,Kojima T, Tanaka R, Okiyama N, Fujisawa Y, Watanabe M, Yamasaki S, Kiyohara H, Watanabe M, Sato TA, Tahara H, Nishiyama H, Yano I. 
    The liposome of trehalose dimycolate extracted from M. bovis BCG induces antitumor immunity via the activation of dendritic cells and CD8+ T cells.
    Cancer Immunol. Immunother, 70: 2529-2543, 2021

  10. Timmer MSM, Teunissen TJ, Kodar K, Foster AJ, Yamasaki S, Stocker BL. 
    Cholesteryl glucosides signal through the carbohydrate recognition domain of the macrophage inducible C-type lectin (mincle). 
    Org. Biomol .Chem.  19:2198-2202, 2021

  11. Lynch AT, Motozono C, Foster AJ, Kodar K, Dangerfield EM, Yamasaki S, Wedlock DN, Timmer MSM, Stocker BL. 
    Trehalose diamide glycolipids augment antigen-specific antibody responses in a Mincle-dependent manner.
    Bioorg. Chem. 110:104747, 2021

  12. Reijneveld JF, Holzheimer M, Young DC, Lopez K, Suliman S, Jimenez J, Calderon R, Lecca L, Murray MB, Ishikawa E, Yamasaki S, Minnaard AJ, Moody DB, Van Rhijn I.
    Synthetic mycobacterial diacyl trehaloses reveal differential recognition by human T cell receptors and the C-type lectin Mincle.
    Sci. Rep. 11:2010, 2021

  13. Nagata M, Toyonaga K, Ishikawa E, Haji S, Okahashi N, Takahashi M, Izumi Y, Imamura A, Takato K, Ishida H, Nagai S, Illarionov P, Stocker B, Timmer MS, Smith DGM, Williams SJ, Bamba T, Miyamoto T, Arita M, Appelmelk BJ, Yamasaki S.
    Helicobacter pylori metabolites exacerbate gastritis through C-type lectin receptors.
    J. Exp. Med. 218: e20200815, 2021

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