業 績 PUBLICATIONS

2023年

  1. Hollwedel FD, Maus R, Stolper J, Iwai S, Kasai H, Holtfreter S, Pich A, Neubert L, Welte T, Yamasaki S, Maus UA.
    Ectopic expression of C-type lectin Mincle renders mice susceptible to staphylococcal pneumonia.
    J. Infect. Dis. jiad608, 2023

  2. Tomiyasu N, Takahashi M, Toyonaga K, Yamasaki S, Bamba T, Izumi Y.
    Efficient lipidomic approach for the discovery of lipid ligands for immune receptors by combining LC-HRMS/MS analysis with fractionation and reporter cell assay.
    Anal. Bioanal. Chem. 2023

  3.  Kawai A, Tokunoh N, Kawahara E, Tamiya S, Okamura S, Ono C, Anindita J, Tanaka H, Akita H, Yamasaki S, Kunisawa J, Okamoto T, Matsuura Y, Hirai T, Yoshioka Y.
    Intranasal immunization with an RBD-hemagglutinin fusion protein harnesses preexisting immunity to enhance antigen-specific responses.
    J. Clin. Invest. 133:e166827​​​​​​, 2023

  4. Matsuoka T, Hattori A, Oishi S, Araki M, Ma B, Fujii T, Arichi N, Okuno Y, Kakeya H, Yamasaki S, Ohno H, Inuki S.
    Establishment of an MR1 Presentation Reporter Screening System and Identification of Phenylpropanoid Derivatives as MR1 Ligands.
    J. Med. Chem. 66:12520-12535, 2023

  5. Oka S, Watanabe M, Ito E, Takeyama A, Matsuoka T, Takahashi M, Izumi Y, Arichi N, Ohno H, Yamasaki S, Inuki S.
    Archaeal Glycerolipids Are Recognized by C-Type Lectin Receptor Mincle.
    J. Am. Chem. Soc. 145:18538-18548, 2023

  6. Ishizuka S, van Dijk JHM, Kawakita T, Miyamoto Y, Maeda Y, Goto M, Le Calvez G, Groot LM, Witte MD, Minnaard AJ, van der Marel GA, Ato M, Nagae M, Codée JDC, Yamasaki S.
    PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand.
    ACS Cent. Sci. 9:1388-1399, 2023

  7. Furukawa A, Shuchi Y, Wang J, Guillen-Poza PA, Ishizuka S, Kagoshima M, Ikeno R, Kumeta H, Yamasaki S, Matsumaru T, Saitoh T, Maenaka K.
    Structural basis for plastic glycolipid recognition of the C-type lectin Mincle.
    Structure 31:1077-1085.e5, 2023

  8. Lorè NI, Yamasaki S, Simmonds RE, Jo EK.
    Editorial: Host-pathogen interactions in nontuberculous mycobacterial infections.
    Front Immunol. 14:1201159, 2023

  9.  Naito Y, Koyama S, Masuhiro K, Hirai T, Uenami T, Inoue T, Osa A, Machiyama H, Watanabe G, Sax N, Villa J, Kinugasa-Katayama Y, Nojima S, Yaga M, Hosono Y, Okuzaki D, Satoh S, Tsuda T, Nakanishi Y, Suga Y, Morita T, Fukushima K, Nishide M, Shiroyama T, Miyake K, Iwahori K, Hirata H, Nagatomo I, Yano Y, Tamiya M, Kumagai T, Takemoto N, Inohara H, Yamasaki S, Yamashita K, Aoshi T, Akbay EA, Hosen N, Shintani Y, Takamatsu H, Mori M, Takeda Y, Kumanogoh A.
    Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation.
    Sci. Adv. 9:eade0718, ​​​​​​​2023

  10. Kodar K, Dangerfield EM, Foster AJ, Forsythe D, Ishizuka S, McConnell MJ, Yamasaki S, Timmer MSM, Stocker BL.
    Aryl-functionalised α,α'-Trehalose 6,6'-Glycolipid Induces Mincle-independent Pyroptotic Cell Death.
    Inflammation 46:1365-1380, 2023

  11. Morita R, Kubota-Koketsu R, Lu X, Sasaki T, Nakayama EE, Liu YC, Okuzaki D, Motooka D, Wing JB, Fujikawa Y, Ichida Y, Amo K, Goto T, Hara J, Shirano M, Yamasaki S, Shioda T.
    COVID-19 relapse associated with SARS-CoV-2 evasion from CD4+ T-cell recognition in an agammaglobulinemia patient.​​​​​​​
    iScience 26:106685, 2023

  12. Ikazaki T, Ishikawa E, Tamashima H, Akiyama H, Kimuro Y, Yoritate M, Matoba H, Imamura A, Ishida H, Yamasaki S, Hirai G.
    Ligand-Controlled Stereoselective Synthesis and Biological Activity of 2-Exomethylene Pseudo-glycoconjugates: Discovery of Mincle-Selective Ligands.
    Angew. Chem. Int. Ed. Engl. 62:e202302569,​​​​​​​ 2023

  13. Watanabe M, Motooka D, Yamasaki S.
    The kinetics of signaling through the common FcRγ chain determine cytokine profiles in dendritic cells.
    Sci. Signal. 16:eabn9909, 2023

  14. Shimizu T, Schutt CR, Izumi Y, Tomiyasu N, Omahdi Z, Kano K, Takamatsu H, Aoki J, Bamba T, Kumanogoh A, Takao M, Yamasaki S.
    Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease.
    Immunity  56:307-319, 2023

  15. Thathsaranie P Manthrirathna MA, Kodar K, Ishizuka S, Dangerfield EM, Xiuyuan L, Yamasaki S, Stocker BL, S M Timmer M.
    6-C-Linked trehalose glycolipids signal through Mincle and exhibit potent adjuvant activity.
    Bioorg. Chem. 133:106345, 2023

  16. Bedard M, van der Niet S, Bernard EM, Babunovic G, Cheng TY, Aylan B, Grootemaat AE, Raman S, Botella L, Ishikawa E, O'Sullivan MP, O'Leary S, Mayfield JA, Buter J, Minnaard AJ, Fortune SM, Murphy LO, Ory DS, Keane J, Yamasaki S, Gutierrez MG, van der Wel N, Moody DB.
    A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages.
    J. Clin.Invest. ​​​​​​​133:e161944, 2023

  17. Yoshikawa FSY, Wakatsuki M, Yoshida K, Yabe R, Torigoe S, Yamasak S, Glen N, Barber GN, Saijo S. 
    Dectin-1/IL-15 pathway affords protection against extrapulmonary Aspergillus fumigatus infection by regulating Natural Killer cell survival. 
    J. Innate Immun.  15:397-411, 2023

  18. Guenther C, Watanabe M, Yamasaki S.
    Immunomodulatory Functions of Glycolipids from Pathogens.
     Methods Mol. Biol. ​​​​​​​2613:23-31, 2023

  19. Nishimura N, Tomiyasu N, Torigoe S, Mizuno S, Fukano H, Ishikawa E, Katano H, Hoshino Y, Matsuo K, Takahashi M, Izumi Y, Bamba T, Akashi K, Yamasaki S.
    Mycobacterial mycolic acids trigger inhibitory receptor Clec12A to suppress host immune responses.
    Tuberculosis(Edinb) 138:102294, 2023

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